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In silico functional comparison between two strains

Can anyone suggest a program that can be ran locally for pairwise functional comparison between strains?

next-gen gene

Can you clarify what you mean by functional comparison between genomes/proteomes?

1 answer

Your question is rather broad, but if you are looking for something general and vast regarding bacterial strains I'd recommend looking into this site: https://www.patricbrc.org/ That platform is really good for bioinformatics starters since it operates fully on a graphic interface; there you can make an account and upload contigs of your strains to annotate them and compare virulence factors, drug targets, proteome, metabolic pathways and many other things. You can even upload raw reads and use the built-in assembler.

Hope this helps.

Thanks very much for your help.

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