This is a test version of Biostars. For the public version, visit https://www.biostars.org.
K-mer analysis meaning

Hi everyone, can you please explain what is a kmer? And what is kmer distribution? And what is the interest of those kmers? Thanks

assembly

What have you tried? Have you tried googling the term? Please edit your question and add some details to show us you have invested some effort and I'll reopen the question.

Hello zahrchefi!

Please see my comment above

For this reason we have closed your question. This allows us to keep the site focused on the topics that the community can help with.

If you disagree please tell us why in a reply below, we'll be happy to talk about it.

Cheers!

Had to be CTB's blog! (Well, either that or dzerbino's thesis on velvet)

Sorry I am not good at english so myquestion was very brief, I want to understand way the assembly softwar fragments the reds into small fragments called kmers? It will be more difficult to assembl those small fragments. Thanks

The blog post should help you understand.

It will be more difficult to assemble those small fragments

What makes you come to this conclusion? Smaller fragments are easier to work with, AFAIK. Even the human eye can discern differences with 5- and 7-mers more easily than with 11- or 13-mers, no?

I dont understand the principle of making kmers. The assembly software fragments itch read into small fragments called kmers and then assembel them? But way the assemby softwar dont assemble the reads directly?

Did you read the blog post?

you need to investigate the using of the de Bruijn graph to explain this.

Certainly, the assembling of genomes using kmers can at least in some cases have certain adventages over the assembling done using the overlapping method

0 answers

No answers yet.

Log in to answer this question.