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Which statistic test is it correct to use to detect common variable within a group of sample?

Good morning,

I'm currently on cancer research and i have several variables for a group of cancer patients. I would like to know which test do I have to apply to detect which of these variables are commons among all patients of my cancer group, so to detect multiple variables that define that group? Do I have to perform a Randome Forest in this case? thank a lot for your help

r statistics
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updated by Jean-Karim Heriche Jean-Karim Heriche • written by AQ7 • AQ7

ah ok I'll use that forum thanks

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written by AQ7 • AQ7

Your question is not entirely clear to me. What do you mean by detecting common variables ? What does your data look like ?

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written by Jean-Karim Heriche Jean-Karim Heriche

well imagine that i have a excel where each column correspond to a clinical value and in rows you have cancer patients and control patients. So i would like to know if one or more than one of these variable is like a "biomarkers" for the cancer patients.

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written by AQ7 • AQ7

1 answer

To identify variables (aka features) associated with one class, look for feature selection/extraction methods in machine learning. I would start with PCA and/or LDA. You could also try a generalized linear model and check the contributions of the variables.

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written by Jean-Karim Heriche Jean-Karim Heriche

thanks a lot for your sugestion. could you please suggest me one of these linear model you are talking about thanks

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written by AQ7 • AQ7

Have look at logistic regression e.g. with the glm() function in R.

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written by Jean-Karim Heriche Jean-Karim Heriche

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