use proovread to correct Pacbio reads with Illumina reads
I am trying to use proovread to correct Pacbio reads with Illumina reads. However, this process costs a very long running time. Is there any way to accelerate this process? I am thinking to normalize the read depth to 30X. Will this significanlt shoreten the running time? Hope there is someone had experience with proovread and your suggestion is very much appreciated.
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Also,when I designated multiple illumina fastq files, it seems that proovread only use the first fastq file for the correction. Do I need to merge all the fastq files before running proovread? Or I am not using proovread right?
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