Human ancestor for hg38 · Biostar

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Human ancestor for hg38

Hi,

I would like to annotate a vcf file based on hg38 with VEP and the LofTEE plugin. However, for LofTEE you need a bgizpped fasta file with ancestral alleles. Currently, I've only found human_ancestor.fa.gz based on GRCh37. Does anyone know where I could get the hg38 version? Does this need to be "liftovered"? Or has anyone done this already?

Thanks M

vep lof loftee hg38 human_ancestor

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written 9.8 years ago by matthias.desmet •

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