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Get REVEL plugin started with VEP

Hello, I am using the VEP tool (version 104) and already managed to annotate a VCF-file (hg19) with basic annotations and CADD. Furthermore I wanted to annotate it with the REVEL plugin. So I downloaded the plugin, as well as the data for REVEL (and preprocessed it according to the information given at the vep website https://m.ensembl.org/info/docs/tools/vep/script/vep_plugins.html).

The following error occurs now when running VEP:

Use of uninitialized value $assembly in hash element at /.vep/Plugins/REVEL.pm line 112. 
Use of uninitialized value in string eq at /home/username/.vep/Plugins/REVEL.pm line 112.

and here is the "REVEL-part" of my vep command:

--plugin REVEL,/home/username/.vep/Plugins/new_tabbed_revel.tsv.gz

and here is the header of the REVEL file after preprocessing it:

#chr    hg19_pos        grch38_pos      ref     alt     aaref   aaalt   REVEL   Ensembl_transcriptid

Coud someone tell me please how to solve this issue?

Many thanks in advance!

Andreas

vcf revel vep

Not yet. Do you have the same problem? Best, Andreas

Have you tried specifying the assembly ('--assembly') in the vep command?

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