Read some papers in NAR database issue.

That's a vague question. "Bioinformatics database" can be anything from an Excel spreadsheet of favorite genes to NCBI. Can you elaborate? What kind of information does it store? How big is it? Does it need to be accessible by a lot of users? Does it require a graphical interface? Is the database management system already defined?

Hello Shicheng Guo!

Based on some recent discussions we have had about vague nature of original questions/posts (which this one qualifies for at the time of this writing) I am going to close this question temporarily until you add some detail to original post.
You should provide a more concise description of what it is you are trying to/want to do. Once you edit your original question we will open this post back up for answers.

For reference this is what the question looked like when the post was closed.

Basic knowledge and basic steps. It would be more appreciated to show some step by step brief introduction.

If you disagree please tell us why in a reply below, we'll be happy to talk about it.

Cheers!