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how to calculate p-value for genes in R

Hello, I have a huge data set of genes I ned to know how to calculate p-values for them, actually i want to use volcano plot, I already calculate fold change now i have to calculate p-values, I will appreciate any help. Thnaks, Neda

r

Exactly what sort of data do you have? A "huge data set of genes" doesn't mean much to us.

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