This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Good text or video explaining what sequence alignment is to an undergrad

I am working with an undergrad, and I need something to explain what multiple sequence alignment is without going too technical into the mathematics behind it.

She is going to align mitochondrial genome sequences for phylogenetic analysis.

alignment
• 2,376 views • link
written by devenvyas 77

Thanks but these are a bit tangential and too technical from what I looking for. I just need to explain to her the concept of aligning multiple sequences from the same locus together (i.e., human mitochondrial genomes), so she can create a sequence alignment using MAFFT to be used in phylogenetic analysis. I think I am just going to show her an old alignment in Geneious and talk her through it.

• 1 views • link
written by devenvyas 77

2 answers

Check Andrew Cowley's materials on the subject for a course he delivered at Cambridge not long ago. If you re-use some of these, please acknowledge the original source.

• 1 views • link
written by Denise CS 525

This is really good. Jump to Slide 50 in the ppt to get to the examples.

• 1 views • link
written by Daniel 397

Alex Baxevanis's annual talks @NHGRI:
and

If you want something more basic


Other videos in the series are here.

• 1 views • link
written by GenoMax 16K

Log in to answer this question.

More posts like this