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Calculate the posteroir probability of Genotype

Hello all, I need understanding of CalculateGenotypePosteriors walker in GATK. Why we calculate this? What will be its significance?

Thanks

gatk posteroir probability genotype
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updated by hoseintoossi • hoseintoossi • written by raya.girish • raya.girish

1 answer

This is to improve genotyping using prior knowledge from known SNP datasets or family relations between the samples in study. If a good quality SNP dataset is available or the family relation between the samples in known, this procedure improves the quality of genotyping. A comprehensive guide to this procedures and how and when to use it is available here.

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written by hoseintoossi • hoseintoossi

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