I have a set of coding variants, on which I want to run some protein protein interaction tools. I've used a couple of resources so far (String, CPDB), and I really want to use Broad's (online) DAPPLE tool. Unfortunately it's been down for some time now, and I can't get a hold of the tool's developers, nor can I find any sources to download so I can run it locally.
My questions - is there anyone here that has used this tool? Could anyone recommend a similar tool, or does anyone have source I could install/run locally?
For reference I've attached a link to a figure generated by DAPPLE, from Neale et al's 2012 article "Patterns and rates of exonic de novo mutations in autism spectrum disorders": http://imgur.com/OvthkiL