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Predicted protein protein interaction FREE tool, insert list of genes and relate to a Single pathway of my interest

Hi All,

I have a list of 2000 genes which I need to relate to the Nfkb pathway, to find if there's any predicted interaction between my target genes and the pathway itself. What I am doing at the moment is using STRING, I insert some genes up- and down-stream of the nfkb pathway and my genes of interesting. Unfortunately this is too tedious and not so accurate, does anybody know a FREE software OR ONLINE tool/plug in which would allow me to upload a longer list of genes and check their relevance in my pathway of interest?

I also tried to use Ingenuity but I'd like a free-easy version

Thanks in advance

predicted-protein-protein-interaction pathway
• 3,247 views • link
updated by Ram Ram • written by MrT11 • MrT11

1 answer

I would propose to turn the query around. Find genes related to the NF-kB pathway using available data and find if your genes of interest are in there. This can easily by done using FUN-L or GeneMANIA: input a list of known NF-kB pathway genes and you'll get back the rest of the genome ranked by relevance to the NF-kB pathway as represented by your query genes.

• 0 views • link
updated by Ram Ram • written by Jean-Karim Heriche Jean-Karim Heriche

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