input gene size in enrichment analysis
Hi there.
I'm new with bioinformatics and I used DAVID for enrichment analysis.
I have two gene sets coming from proteomic approach, (two different gene size lists 84 and 49) and DAVID gives me back a number of enriched terms with their BH corrected p-values. Does input gene size influence enrichment p-values? Can those enrichment analysis be compared somehow?
Thanks in advance
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1 answer
Ofcourse it does influence. Please check how the statistics work in this case...
https://github.com/santhilalsubhash/geneSCF/wiki/Statistical-methods-used
The statistics in the provided link is used by a gene enrichment tool called GeneSCF. This is almost similar to what DAVID uses.
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