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Pre-phasing for imputation BEAGLE or MACH

Hello,

I'm performing pre-phasing for imputation in MACH. However, this is very time consuming. There are 950 individuals and for chromosome 4, there are ~37.000 SNPs, for example.

I've read that BEAGLE is faster but less accurate depending on sample and marker size. In this case, do you think using BEAGLE would be a problem?

phasing imputation beagle mach

1 answer

Check out SHAPEIT.

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