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HAPLOTYPES SOFTWARES interpretation

Hello, I used two software tools to analyze haplotypes: haploview and phase. I found positive results with the Phase software but not with the Haploview software. I'm not familiar with these two programs so I don't know if it is ok to find this difference. Thank you a lot for your help.

snp genome gene
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updated by Ram Ram • written by sabrinedhouioui • sabrinedhouioui

Welcome to Biostars. Please be more specific:

  • what do you mean by positive results
  • please provide an example case and describe your experimental data used for the analysis

Otherwise we cannot help you as it is to be expected to obtain different results form different software.

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updated by Ram Ram • written by Michael Dondrup Michael Dondrup

OK. I'm sorry for the ambiguity of my first question. I studied the possible influence of IL-8 , -10 and 4 in breast cancer progression. So I used the Haploview and PHASE software tools for the construction of haplotypes. When I analyzed the PHASE results, I found that one of the obtained haplotypes is associated with the disease but not with Haploview software because there is no linkage disequilibrium. Based on these results, I didn't know if it is ok to say that the haplotype obtained is linked to progression in breast cancer (because there is a difference between these two results).

Thank you for your response.

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updated by Ram Ram • written by sabrinedhouioui • sabrinedhouioui

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