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pVAAST Complex Disease

Does anyone have any recommendations for parameters to set when using pVAAST to analyze multiple pedigrees in a complex disease model?

Thanks,

Steven

genome sequencing gene next-gen

Do you have a list of which parameters need to be set?

Sure, my main concern is which variants to select for testing (i.e. do I select to look at genes only from affected family members, or do I take a union of the contents etc.) Alas, there are others as well but I'm simply not familiar enough with how the program works to really understand their function

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