Dear Biostars,

I need to annotate my human exome sequenced dataset with gnomAD v4 so that I am using a relatively up-to-date summated control dataset for rare variant analyses.

gnomAD v4 recommends working with Hail to annotate. Unfortunately, while I have annotated with other datasets I have no experience with Hail or indeed python and am finding this very difficult.

Would anybody be willing to post or send me an excerpt from a pipeline or some code where this has been done that I might use this as a template?

Many thanks for your time.

James