What does it means, when 2-direction perturbed pathways are identified in the gage enrichment analysis?
The gage method for enrichment analysis using ENTREZ Ids emphasizes on its capability to test for changes not only for up- and down-regulated pathways, but also for those with a 2-directional change.
I don't understand what this means biologically. Does it mean that the pathway is being significantly deregulated in both directions simultaneously, or that it contains genes that that show a deregulation in both directions?
thanks
• 671 views
•
link
written
by
Assa Yeroslaviz
0 answers
No answers yet.
Log in to answer this question.
More posts like this
-
Correct way of doing enrichment analysis (ORA)
written by carolofharvest •
-
Both up- and down-regulated gene sets return the same GO pathway analysis results?
written by xqyn •
-
Extract/include transcript list from GAGE analysis result
written by farzaneafzali •
-
KEGG pathway gene lists differ between sources
written by aedan.r •
-
Converting REFSeq IDs to Entrez IDs for KEGG analysis - "geneid of incorrect length"?
written by saw44 •
-
How to answer if the biological process is up or down-regulated?
written by aln
-
Same KEGG pathways enriched by up- and down-regulated genes
written by mahmeh •
-
Using GAGE to Analyze Pathway Enrichment Directly from Fold Change Data
written by JMallory •
-
GAGE pathway analysis for RNA-seq
written by Ming Tommy Tang
-
Normal Distribution Of (Log) Microarray Results
written by Assa Yeroslaviz
