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How to remove batch effect from TCGA RNA-seq data?

Hello,

I have input of 23000 genes of data table and run blockwise module. It shows that one module has 17000 of genes clustered. I don't know how to remove batch effect which I read from other researchers's paper. enter image description here

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batch-effect wgcna

1 answer

there is a recent paper on this https://www.nature.com/articles/s41587-022-01440-w

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