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I need help with a methyl array data analysis

I have methyl array data in beta value of 2 groups of sample, how I can stat the downstream analysis by r to get DMPs and DMRs?

beta value

methyl_array dmps dmrs beta_value r
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written by Ahmad • Ahmad

Thank you, I will check it out

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written by Ahmad • Ahmad

It seems the data appears to be in the beta value format (?), which represents the proportion of methylated probe intensity over the total (methylated + unmethylated) probe intensities. One note regarding your data, it is important to have replicates in your samples to increase the statistical power and robustness of your results.

Is your data in the dataframe (df)?

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written by Decimus Maximus • Decimus Maximus

I actually have replicates.

thank you

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written by Ahmad • Ahmad

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