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how to deal with missing genotype data (gt) to do a machine learning

hi

I have a missing genotype data ./. and I want to encode genotype data to do machine learning algorithems

So I have 0/0 , 1/1 , 0/1 and ./. how can i encoded to do ML algorithems

thanks.

missing_data

What is the scientific question you're trying to answer ?

you can 1) naturally encode them as NA , NA is a special value to encode missing information "Non Available", 2) impute the missing genotypes prior to any downstream analysis.

how can I impute the missing genotypes? Is there any methods for imputing? Can u help me

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