Types of SNPs naming related to GWAS
Hi, I would like to start a post-GWAS functional analysis and would like to get some clarification about the definition of SNPs, identified from GWAS.
Tag SNPs - representative single nucleotide polymorphism (SNP) in a region of the genome. Usually lowest p-value.
LD SNPs - SNPs in linkage disequilibrium with the tag SNPs. Equally causative.
Fine-mapped SNPs - a credible sets of SNPs in a region.
Near-independent SNPs - obtained from the conditional analysis. Contained secondary signals of the original GWAS SNPs
Please correct me if I am wrong.
Thank you.
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austin7923 •
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