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Best tools for scTCR-seq (VDJ) analysis?

Hello,

I will analysis scTCR-seq datasets of single-cell immune receptor receptor.

Which one is the best tool for VDJ data analysis? VDJ tools, clonotypr, VDJServer, VDJML or scRepertoire?

Thanks in advance for great help!

Best Wishes,

Yue

sctcr-seq
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updated by Ming Tommy Tang Ming Tommy Tang • written by yueli7 yueli7

What types of question do you have?

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written by Friederike Friederike

Hello Fridederike,

Thank you for your message. I want to ask which one it the best tools for analysis scTCR-seq data?

Thank you in advance for your great help!

Best,

Yue

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written by yueli7 yueli7

Yue,

...best tools for analysis scTCR-seq data?

Analysis begins with questions, not tools. Friederike is asking, "what are the questions you are asking of your data?" so that we can then form ideas about what tools would best answer those questions.

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written by seidel seidel

Hello Seidel,

Thank you for your message!

I made the change.

Thank you again!

Best,

Yue

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written by yueli7 yueli7

2 answers

I have collected a bunch of tools at https://github.com/crazyhottommy/TCR-BCR-seq-analysis

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written by Ming Tommy Tang Ming Tommy Tang

Since series 4 MiXCR software supports single-cell. It is also very easy to use and it supports most of the commercial single cell protocols and can be customized.

https://docs.milaboratories.com/mixcr/reference/overview-built-in-presets/

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written by mizraelson • mizraelson

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