I want to know the difference between Genome Reference in scRNAseq and transcriptome reference in bulk RNAseq.

But I didn't get any better answer in any other place.

I know we could download genome reference from UCSC, NCBI, ENSEMBL and GENECODE for bulk RNAseq. And here are the links below:

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GENCONDE GENCONDE2

UCSC

ENSEMB

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Also ,I find the genome reference links for scRNAseq in Illumina(a link summary page):

Illumina We can download these resource for scRNA sequencing.

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Besides, 10x provides us its own link for scRNA seq: https://support.10xgenomics.com/spatial-gene-expression/software/downloads/latest

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However, I don't know the exact difference between genome reference in scRNAseq and transcriptome reference in bulk RNAseq except the file size.

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And, I have read the question here:What Is The Difference Between Genome Reference And Transcriptome Reference? and @Chris Miller answered its question. He said : Transcriptome references generally consist of only the coding regions of the genome. This may include genes with all of their introns spliced out, as well as all known transcripts of a gene, including alternate starts or splice junctions, exon skipping, etc.

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My QUESTION is if I can use the same genome reference and gene annotation files ? For example, could I only use the genome reference and gene annotation files downloaded from UCSC in scRNAseq ?

Or I should distinct them by scRNAseq and bulk RNA seq ?

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