Alternative splicing in gencode annotations
Hi there,
I don't quite understand how alternative splicing looks like in a gencode annotation. Is it each transcript? or just the transcripts of type "retained_intron" or "disrupted_domain"? or should I be looking at the positions for each annotated gene? or maybe I should look at the exon numbers? maybe something else?
I hope someone can help me understand this.
Julian
• 1,149 views
•
link
1 answer
It is in the comparison of transcripts. When you compare two transcripts you can see which splicing was needed to produce this transcript. Another approach is to compare a transcript with the hypothetical pre-mRNA you get by combining all exons (excluding retained introns).
• 0 views
•
link
Log in to answer this question.