Smoothing r binning bigwig plots in R

What are R tools/packages I can use to smooth a bigwig plot? I basically want to get bam coverage as bigwig files for every 100bp regions. I am using rtracklayer and genomicAlignment packages to convert bam to bigwig files.

bigwig r bam

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updated 4.7 years ago by ATpoint

• written 4.7 years ago by star715 •

Check the genomation package from Bioconductor which has a ScoreMatrixBin() to load coverages from bigwig files and bin it over specific intervals.

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written 4.7 years ago by ATpoint

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