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Chip-Seq Analysis: How To Pair Plus And Minus Strand Peaks

After peak calling with GeneTrack, how to pair plus and minus strand peaks if peaks are on 3' end to each other & < 100 bp apart. I also want to know, how to normalize ChIP-exo data such that total tag count inside of background regions are same. background regions are defined as any region that lacks a peak pair within 100 bp.

normalization

2 answers

You can use bedtools to perform various kinds of interval operations.

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