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Is There Any Tool For Drawing A Gene/Protein Diagram?
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10.1 years ago
Daniel ▴ 50

Is there any tool for drawing a diagram of the "anatomy" or structure of protein/gene domains just like the figures normally shown in articles?

visualization • 16k views
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Could you link to some example figures that illustrate what you want?

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9
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10.1 years ago

If you are looking at 2D, schematic diagrams like the following figure: alt text You can use My Domains.

Similar schematic diagrams can be generated from protein structure (seee the following figure) data using DOMPLOT.

alt text

If you are looking at 3D structure visualization of your gene/protein: Try one of the following tools:

  • PyMol: Educational use is free, limited options
  • Molscript / Raster3D: Very powerful visualization programs, command-line.
  • Jmol: Web based, Java applet
  • Several other tools are available here and here

See an example MolScript figure below:

alt text

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Nice list! Thanks for adding some color to the weekend

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Nice list, thanks for adding some color to my weekend

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Glad to note that :) !

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3
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10.1 years ago

If you like coding, you could also give TiKZ a try: http://www.texample.net/tikz/examples/area/biology/

TiKZ has a steep learning curve, but once you get the hold of it, making nice illustrations become really fun.

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6.8 years ago
jeffk8900 ▴ 130

You can use the newly released lollipop tool from cBioPortal team. Just modify input to include header and gene name for protein of interest:

Hugo_Symbol    
AR    

The resultant protein diagram can be edited in SVG editor to remove extraneous graphical elements.

Tool can be founder here:

http://www.cbioportal.org/public-portal/mutation_mapper.jsp

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