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Transcription Factors <--> Regulated Genes Database

Hi,

I'm looking for a publicly accessible database that stores transcription factors to regulated genes relationships.

Ideally, I'm looking for something like:

TF1 geneX
TF1 geneY
TF1 geneZ
TF2 geneY
TF3 geneX
TF3 geneA
... ...

Is anything like that available?

Thanks!

database transcription-factor gene
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updated by Ram Ram • written by enricoferrero enricoferrero

For what organism? Are you interested in all transcription factors, or only those thought to be expressed at a certain time point or in specific tissues? Or in one gene regulatory network? I am not aware of a tool that pools together all TF - target data. One thing you can do is script off of the GEO datasets -- if there are specific TF's you are interested in, someone may have made a mouse KO, studied gene expression, and the data will be posted to GEO. You can infer some targets that way. (But this will require some normalization statistics across experiments/platforms -- and it's still an inference.)

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written by Alex Paciorkowski Alex Paciorkowski

1 answer

Hi enricoferrero,

I know this is a long halted question and a thread. However, I'm really interested to know whether you achieved what you wanted to achieve. If so, can you please share your ideas with us rest of stumblers upon the same question? Thanks a lot.

Shani.

P.S. I'm looking at the Arabidopsis TFs and their target genes. If anyone knows where to look, please guide me through. I already tried the AtRegNet, but still I'm not sure that is exactly what I want.

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updated by Ram Ram • written by shanika.amarasinghe • shanika.amarasinghe

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