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Hi All,
If we have some step by step tutorials for GWAS analysis ? Like I have VCF files and how to start from here ? I know its very basic question but I didn't work on GWAS till now either !!
3 answers
Search this site for GWAS tutorials and see posts like this:
Following links are in addition to what Istvan recommended. They do not have step by step guide, but rather explain the scientific aspect of what GWAS researchers do.
As a starter, please check this book by professor Ken Weiss.
He also writes a very informative blog at http://ecodevoevo.blogspot.com/. Not all comments are directly related to GWAS, but you can check his today's writing on cystic fibrosis for example.
http://ecodevoevo.blogspot.com/2013/08/cystic-fibrosis-genetic-variation-and.html
We covered his blog and issues related to GWAS here:
http://www.homolog.us/blogs/blog/2013/07/30/battle-over-gwas-ken-weiss-edition/
Also, Finch and the Pea blog posts informative commentaries on GWAS-related scientific issues. Please check
"We still don’t know why children resemble their parents"
http://thefinchandpea.com/2013/08/23/we-still-dont-know-why-children-resemble-their-parents/
Remember, science advances through consensus. Biggest advances like Darwin's theory and Mendel's discoveries were immediately accepted by the najority, and were widely 'retweeted' as soon as they appeared :)
Hi All, Thanks all !! I made a very good progress on this !! Thanks every one !! But I have some very basic doubt still :
1) How do we get files .bed and .map format ? [ I guess that we will convert vcf files to .bed format then what about .map format ]
2) How to do check if data has passed all standard checks? [ Any tool for this ]
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