I am wondering if there is any modern implementation of RNAShuffle program described in this manuscript from circa 99 is available somewhere. www.ncbi.nlm.nih.gov/pmc/articles/PMC148359
A program (RNAshuffle) was written in FORTRAN using the GCG software library that randomized only the codon choice to produce ‘codon-random’ sequences for the fourth randomization procedure. Codon-random sequences have the same nucleotide base composition and translated polypeptide product as the respective native mRNA.
I need to do the same task for a couple of mRNA sequences. So just checking if anyone have this already implemented or available as part of any of the bio-* libraries.
Thanks in advance !