Hi Sarah,
can I do this graph viewer automatically using R? I need to do this picture for several groups of GO term and I would like to do it using an script automatically.
Thanks in advance
Isabel
I have some lists of gene annotation come from the Gene Ontology. Every annotation is a coupling <gene, feature> where the feature is a Gene Ontology term. Every term is a node in the Gene Ontology tree.
I need a tree visualization tool to depict the Gene Ontology tree of that term, and so understand in which tree level is the analyzed term.
Something like this picture:
Can you suggest a tree viewer software that could be useful to me to solve this issue?
Thanks a lot!
Hi,
You're not looking for a tree viewer, you're looking for a DAG viewer ;-) In your example, if it were a true GO graph, E would, for example, be a child of D and I.
The EBI's QuickGO tools allows you to do what you want.
For example, I selected a few terms that were related to Apoptosis and generated the following ancestor chart for comparison: http://www.ebi.ac.uk/QuickGO/GMultiTerm#a=64%240AaC0E%5Bq0Nkg&tab=chart&c=
Instructions:
Hope this helps!
Sarah
Hi Sarah,
can I do this graph viewer automatically using R? I need to do this picture for several groups of GO term and I would like to do it using an script automatically.
Thanks in advance
Isabel
There are cytoscape plugins, one such is ClueGO.
You may want to check FDA's GOFFA tool.
website: http://www.fda.gov/ScienceResearch/BioinformaticsTools/ucm233315.htm
Paper: http://www.biomedcentral.com/content/pdf/1471-2105-7-S2-S23.pdf
I built a graph viewer for gene ontologies with D3.js and some python scripts, following this blog post. You can do it too.
I also built a graph viewer with the vivagraph javascript library, it is much more efficient (thanks webgl) but less flexible.
I think there is also some GEPHI tools to do that.
If you are really interested, i can give you some advices.
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