This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Review Papers On Short Read Mapping?

I'm teaching a course on computational genome science and next week we're focusing on short read mapping. I'm familiar with and/or have used some of the more popular mapping tools (Bowtie, BWA, Novoalign) as well as related tools for various downstream applications (Tophat/Cufflinks, Novomethyl), so I feel prepared to at least cover the basics. However, I'm curious whether there are any recent review papers that discuss the mapping problem, the various approaches used to solving it, and/or the biological questions scientists are trying to answer with these tools. Any recommendations?

mapping ngs
• 5,288 views • link
updated by Botond Sipos Botond Sipos • written by Daniel Standage Daniel Standage

3 answers

Nuno A. Fonseca, Johan Rung, Alvis Brazma and John C. Marioni (2012) Tools for mapping high-throughput sequencing data. Bioinformatics 28:3169-3177. doi:10.1093/bioinformatics/bts605

It is quite comprehensive and comes with a regularly updated online compendium of mappers.

• 73 views • link
written by Botond Sipos Botond Sipos

This is exactly what I was looking for. Thanks!

• 0 views • link
written by Daniel Standage Daniel Standage

They're both slightly dated and don't have the latest and greatest tools, but the motivation and descriptions are still on target. You might complement these reviews with a well-written recent paper like the GEM, bowtie2, or bwa-mem manuscripts.

• 112 views • link
written by matted matted

A solid quality-control analysis of AB SOLiD short-read sequencing data.

http://www.ncbi.nlm.nih.gov/pubmed/22877770

• 0 views • link
written by Leandro Lima Leandro Lima

Log in to answer this question.

More posts like this