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Shrimp2 For Rna-Seq

I was wondering if I can use SHRIMP2 for RNA-seq alignments of a viral genome? I have not see any paper on this and wonder if I am thinking it rightly or it is mainly used in DNA seq variation analysis?

rna-seq alignment

1 answer

In many cases RNAseq means you need some way to map reads with spliced regions, but for virus, the genes are transcribed in one exon (not true for a few species which have exon-shuffling), so you don't need to split your reads. SHRIMP2 is a general genomic mapper focused principaly on ABI/SOLiD, I think it can work for you as any other mapper.

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