IGV or IGB

Question

[akivab2]

Hi,

In the past I used to work with IGB, mainly for DNA-seq. I started working in a new lab, and the genome browser they have been using is IGV. Much of the data viewed in the lab is of RNA-seq and ATAC-seq.

I was wondering if there is any preference to IGV or IGB? I found IGB to be easier to use and visually nicer, so I rather continue using it, unless of course there is some advantage to IGV.

Thanks, Akiva

P.S. i read somewhere that IGV is better for NGS data, is this true? and why?

[GenoMax]

I am sure you will find people who strongly feel about one or the other but I don't think there is a clear winner. IGV is probably better funded, promoted and thus used than IGB but that is a non-technical distinction.

It finally is personal preference.

[Nowlan Freese]

Both projects are currently funded and actively developed.

Answer 1

[xunshengbu]

I used IGV a lot and recently checked up IGB. Both have basic gene features and sequence visualization. IGV offers a lot of visualization features on variations (VCFs), which I haven't see much on IGB (doesn't mean it's not there). IGB does have on-the-fly plugins, allows you to compare known SNPs in 23andMe, or blast gene of interest to NCBI NR database, and InterProScan on annotation (haven't tried yet).