Problems With Firehose_Get Of Tcga Brca Wig File

Question

[yliubu]

Hi, everybody,

I am now trying to download TCGA wig file for each cancer type, but it seems that only OV and GBM have valid WIG files. For BRCA, there is only 1 wig file. If I need the coverage information of each sample for breast cancer, what should I do? Thanks.

[Michael]

Please spell out your acronyms! Please provide background about the biological question you are trying to address, so we understand why you need coverage information of samples (that can mean different things, eg. from RNA or DNA sequencing?), which samples are you referring to anyway?

[yliubu]

I am now trying to use MuSiC to calculate BMR of BRCA of TCGA. One input requirement of MuSic is the coverage of each sample from wig file, which can be downloaded using firehose_get. But when I download OV or GBM data, there are coverage wig file for each sample, but for BRCA, there is only one wig file. So I am wondering if I want the coverage information of other samples, what should I do? Thanks.