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Comparative Genomics In Hmp

How does comparative genomics of bacteria in the Human Microbiome Project (HMP) help us to understand and cure Human Infection or find specific drug Targets?

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Please rephrase your question. Add context.

Agreed. Without context of why you are asking this and what you are trying to do, this reads like a homework question. I suggest you explore the HMP website and the publications they list. Many of which will likely address your question.

Rather than post as an answer to your question, you should have made a comment here and edited your question to now include these specifics. Then hopefully someone more familiar with this area of research can help you. You might also clarify what specifically are the "different niches" to which you refer and what you mean by having COGs data.

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