I want to generate Position Specific Scoring Matrix and later to derive features from it for my application. I am using standalone blast algorithm PSI …

Hi, I was wondering if anyone knows if there is a default protein database linked to the MAF files of the TCGA project? Basically what …

<p>Hi, I want to compare protein homology detection quality of my algorithm with psi-blast and delta-blast algorithms. Mainly I'm interested in calculation of Sensitivity, Specificity …

<p>Hi everybody, I have HIV reverse transcription gene mutation samples .also I have mutation information and corresponding drug resistance of each sample. I want to …

<p>How to calculate a vector of features to predict the effect of mutation on protein stability? Assume I have protein sequence mutation , wild type …

<p>Hi,</p> <p>am trying to "predict the effect of mutation impact on protein function", am trying to get features to achieve the prediction. I wonder what …

<p>Hi, I wonder how I can use mutant residue or wild type residue and position with blastpgp. Does it have parameters to accept any of …

<p>I want to know how to call Blast from java code, I have wildtype residue, mutant residue, position of mutation, and protein sequence</p> <p>I want …

<ol> <li><p>I want to pass a protein sequence using java code to find the relative frequency of wildtype residue in PSI-BLAST alignments</p></li> <li><p>Also I would …

<p>Appears that there is a misunderstanding on my part, and this question is an attempt to sort out these conflicts.</p> <p><strong>Definitions:</strong></p> <ul> <li><strong>Protein change</strong> being …