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SarsCov2 annotation database

Hello!

When sequencing SarsCov2 viruses we get a number of variants, and it would be interesting to see if these variants are already reported and where, or use it as a filtration criteria. Is there an annotation database, ideally as a vcf like dbsnp, that could annotate resulting mutation VCFs for viral whole genome sequencing?

Thanks!

viral sarscov2 annotation

it would be interesting to see if these variants are already reported

They have probably been reported. Question is are they in a place/form that you can query/use. GSAID/NCBI both have thousands of genomes now and since it is only a 29kb genome we should have seen most of changes by now.

2 answers

Look at the COVID19 data portal variants section.

Thank you, this is a great suggestion. Still, I can't fine a usable database or VCF file to use wtih an annotator, is there such a thing that you know of? I went further to ensembl, but I don't get around easily there.

You could use Ensembl VEP tool with the right data/annotation.

Thanks, that is the idea, but I can't find a VCF for that, or do you know how to use a plugin that doesn't require it?

If you are not going to have your own VCF to annotate then using a public mutation database like one @Jean-Karim linked would be your best bet.

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