Is it possible to infer tumor purity from tumor-specific Variant Allele Fraction (VAF)?
Is it possible to infer sample's tumor purity form the distribution of its tumor-specific VAFs alone?
Sorry for the lack of prior information, but I was told, from an expert on tumor genome analysis, that it is indeed plausible.
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Only if your tumor is far from 100% purity (say, 90%). Otherwise it is not really reliable.