Why cai_for_gene method substracts one from cai_length in biopython

I am learning how to calculate CAI and how to implement it in Biopython.
I don't know why cai_for_gene method in CodonAdaptationIndex class subtracts 1 when calculating CAI.
Can someone please tell me why? Thank you.

https://github.com/biopython/biopython/blob/master/Bio/SeqUtils/CodonUsage.py#L157

Biopython: version 1.78

biopython python

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updated 5.8 years ago by Biostar

• written 5.8 years ago by yamasakih •

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