The main difference between SIFT and PolyPhen-2

I was wondering what the main differences are between the methods used to make the predictions with SIFT and PolyPhen-2? When analyzing SNPs, what could be the potential reason if the result of the 2 methods don't agree with each other?

snp

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written 5.8 years ago by radinms •

What do the SIFT and Polyphen2 publications say?

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written 5.8 years ago by Ram

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