I am using mitochondrial PacBio data and would like to know how to calculate the species-specific mutation rate of mitochondrial DNA for my species.? I …

Hello experts, I was reading > 'Bierne, Nicolas, and Adam Eyre-Walker. "The problem of counting sites in the estimation of the synonymous and nonsynonymous substitution …

Hi, I've downloaded SNV data (.maf file) for TCGA-SKCM. There is no column in data for mutation frequency. Now, for each gene I've to calculate …

Can anybody tell me how to calculate the mutation rate of a protein sequence of bacteria? Is there any tool or software for the same?

Hi, I am using some tools (VCTtools, or PopLDdecay) to calculate LD decay of drosophila, and I am thinking can I use the results of …

I have some doubts about How can I work with my fasta sequences...I want to measure my sequences mutation rates?What can i do for it?I …

Hi guys, I am using mutation data in ICGC. There is a mutation type named "multiple base substitution". Please refer to an example at https://dcc.icgc.org/mutations/MU63993950 …

Hello, I have made a codon alignment using pal2nal and generated a .codon file. Now I want to calculate the dN/dS values using paml. How …

Hi, I wonder what does it exactly mean when the neutral theory of molecular evolution predicts that at neutral sites, the rate of substitution is …

<p>Hi all,</p> <p>I want to calculate the mutation rate for a codon using the mpileup files I generated from paired end reads.</p> <p>I have 60 …