Hi everyone,

I have two questions regarding the SRA database:

I am trying to get hold of single cell DNA sequence data from colon carcinoma. There is a great dataset stored in SRA PRJNA319560 which contains data from two patients CO8 and CO5.

There are numerous files/runs for each patient, I have trouble making sense of them:

1. How can I get hold of a e.g. barcoded BAM file out of these files? Do I have to download all separate files and comprise them somehow?

2. Where can I find matched non-tumor samples? I have seen several publications using this dataset and mentioning matched normal-data, but I can't seem to find those in SRA.

Thanks ever so much for your help!

Best wishes