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how can i evaluate the different between two samples of distribution of peaks in the genome of chip-seq

Hi i showed the heatmap of TSS region used Deeptools, and found there was a different between two samples, however, how can i get a statistic(p value or fold change?) to indicate the difference? thank you for your help! enter image description here

chip-seq

As far as I am aware, there is no standard, broadly applicable way to put a p-value on the difference between samples in these sorts of analyses.

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