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GCTA-COJO slct conceptual question

Hello,

I was wondering if anyone could clarify something about GCTA- COJO, specifically COJO-slct I think.

I understand that it is a tool that performs stepwise model selection to select independently associated SNPs. Does it first identify index SNPs upon which to condition? Or do I need to identify index SNPs first through LD clumping?

Background is that I've done a meta analysis on a few cohorts and want to identify independent SNPs.

Thank you!

snp

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