Hi, I was just wondering if anyone has seen a genome coverage histogram as the green one and have any explaination for the same? This …

Hi, What is the correct way or best practice to choose allele frequency thresholds to separate rare from common variants when your cohort is less …

Hi, Can anyone recommend a tool or software suite (free of course) that can be used to perform mode of inheritance based filtering for trios …

Hi, This must be a pretty straightforward question, but just wanted the views of the community. We have sequenced (paired-end) multiple samples in a target …

Hi, Can any experienced exome sequencing analysis/variant calling person let me know how many reads out of total reads do you expect to be outside …

Hi, Mapping short reads to human genome primary asembly (GRch38) can become messy due to the presence of alternate contigs. Hence, genomes without alternate contigs …

Hi, I have SNP data from an array which has coordinate information from an older version of the genome (in VCF form). I want to …

Hi, I am using tabix vcf(gz) and index files (gz.tbi) from cache server which assign them some casche id rather than real name. sample.vcf.gz ----> …

From what I understand tabix, vcftools and bcftools make different types of indexes. vcftools makes `.idx` files whereas tabix makes `.tbi` files. Is there a …

<p>hi all. i am generating a vcf file as the end result of my processing and i want to perform an interval query. since, tabix …