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Can I use a logistic regression to test the presence/absence of phylum between healthy-diseased?

Hi, all.

I'm analyzing the OTU table now and want to know whether the phylum specifically exist in the Healthy or the Diseased.

To do so, I carried out a Logistic Regression with binary dependent variable (1: Presence, 0: Absence) and State (Healthy - Lightly Diseased, Healthy - Heavily Diseased) as explanatory variable.

Do you think it makes sense? If not, what else I can use??

Thank you all :)

r statistics microbiome
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updated by Biostar Biostar • written by pple2202 • pple2202

Hey, thank you for your reply. I thought regression would be more practical and commonly used so that's why I used it. Would it be better with using Chi-square test for association test?

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written by pple2202 • pple2202

That would be my first choice and is actually simpler than doing regression.

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written by Jean-Karim Heriche Jean-Karim Heriche

Thanks a lot for your comment :)

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written by pple2202 • pple2202

Hi, can I ask one more? I get the statistical significance of their presence but how can I know their direction? Like which one is more likely to be present in the Healthy or diseased?

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written by pple2202 • pple2202

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