This is a test version of Biostars. For the public version, visit https://www.biostars.org.
How does imputation software calculate haploid alternate allele dosage from posterior probabilities for genotypes?

I am performing imputation with minimac

I get this result for one field

Genotype :                                                                                  0|1
Estimated Alternate Allele Dosage [P(0/1)+2*P(1/1)]:                                      0.929
Estimated Haploid Alternate Allele Dosage:                                          0.046,0.883
Estimated Posterior Probabilities for Genotypes 0/0, 0/1 and  1/1              0.111,0.848,0.041

I get that the Estimated Alternate Allele Dosage .929 is calculated by (.848 + 2*.041)

I don't get how they calculate haploid alternate allele dosage. Does anyone know?

impuation

0 answers

No answers yet.

Log in to answer this question.