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Main Methods Used To Predict Functional Annotations In Go

Can someone provide me some information about the main method used to predict the inferred electronic annotations in Gene Ontology?

prediction annotation
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updated by Emily Dimmer • Emily Dimmer • written by 9606 9606

2 answers

This paper ( http://bib.oxfordjournals.org/content/12/6/723.full ) says that the majority of IEA-annotations come from the GOA-database annotation pipeline, which is based on four sources: UniProtKB/Swiss-Prot Keywords2GO, EC2GO, HAMAP2GO and InterPro2GO. For more information, check out their paper: http://nar.oxfordjournals.org/content/37/suppl_1/D396.full

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written by Philipp Bayer Philipp Bayer

Phillip is spot on in his reply. You can see the breakdown of annotations by different sources/methods in the latest UniProt release here: http://www.ebi.ac.uk/GOA/uniprot_release.html

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written by Emily Dimmer • Emily Dimmer

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